EFFECT OF ALCOHOL ON THE BLOOD.

February 7, 2010 · Posted in Miscellaneous 
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Dr. Richardson, in his lectures on alcohol, given each in England and America, speaking of the action of this substance on the blood once passing from the stomach, says:

“Suppose, then, a sure measure of alcohol be taken into the abdomen, it can be absorbed there, but, previous to absorption, it can should bear a correct degree of dilution with water, for there is this peculiarity respecting alcohol when it is separated by an animal membrane from a watery fluid just like the blood, that it will not labor under the membrane until it has become charged, to a given purpose of dilution, with water. It’s itself, of course,  therefore greedy for water, it can decide it up from watery textures, and deprive them of it till, by its saturation, its power of reception is exhausted , once that it can diffuse into the current of circulating fluid.”

It is this power of absorbing water from each texture with that alcoholic spirits comes up-to-date, that creates the burning thirst of those who freely fancy its use. Its effect, when it reaches the circulation, is thus described by Dr. Richardson:

“Because it passes through the circulation of the lungs it is exposed to the air, and a few little of it, raised into vapor by the natural heat, is thrown off in expiration. If the amount of or not it’s large, this loss might be considerable, and the odor of the spirit might be detected within the expired breath. If the number be small, the loss can be comparatively very little, because the spirit will be held in resolution by the water in the blood. Once it has knowledgeable the lungs, and has been driven by the left heart over the arterial circuit, it passes into what’s called the minute circulation, or the structural circulation of the organism. The arteries here extend into terribly small vessels, which are referred to as arterioles, and from these infinitely little vessels spring the equally minute radicals or roots of the veins, that are ultimately to become the good rivers bearing the blood back to the heart. In its passage through this minute circulation the alcohol finds its means to every organ. To the present brain, to these muscles, to these secreting or excreting organs, nay, even into this bony structure itself, it moves with the blood. In a number of these components which aren’t excreting, it remains for a time subtle, and in those components where there’s a large proportion of water, it remains longer than in different parts. From some organs which have an open tube for conveying fluids away, because the liver and kidneys, it is thrown out or eliminated, and in this approach some of it is ultimately far from the body. The remainder passing round and spherical with the circulation, is probably decomposed and carried off in new types of matter.

“When we understand the course that the alcohol takes in its passage through the body, from the amount of its absorption to that of its elimination, we have a tendency to are the better ready to evaluate what physical changes it induces in the different organs and structures with which it comes in contact. It 1st reaches the blood; but, normally, the amount of it that enters is insufficient to produce any material effect on that fluid. If, but, the dose taken be toxic or semi-poisonous, then even the blood, made as it’s in water and it contains seven hundred and ninety components during a thousand is affected. The alcohol is diffused through this water, and there it comes connected with the other constituent elements, with the fibrine, that plastic substance which, when blood is drawn, clots and coagulates, and that is present in the proportion of from two to three components during a thousand; with the albumen that exists within the proportion of seventy components; with the salts that yield regarding ten components; with the fatty matters; and lastly, with those minute, spherical bodies which float in myriads in the blood (that were discovered by the Dutch thinker, Leuwenhock, mutually of the primary results of microscopical observation, regarding the center of the seventeenth century), and which are called the blood globules or corpuscles. These last-named bodies are, in fact, cells; their discs, when natural, have a smooth define, they are depressed in the centre, and they are red in color; the colour of the blood being derived from them. We have discovered that there exist alternative corpuscles or cells within the blood in a lot of smaller amount, which are called white cells, and these different cells float within the blood-stream inside the vessels. The red take the centre of the stream; the white lie externally near the edges of the vessels, moving less quickly. Our business is especially with the red corpuscles. They perform the foremost vital functions in the economy; they absorb, in great part, the oxygen which we inhale in respiration, and carry it to the extreme tissues of the body; they absorb, in nice half, the carbonic acid gas which is produced within the combustion of the body in the intense tissues, and produce that gas back to the lungs to be exchanged for oxygen there; in short, they are the very important instruments of the circulation.

“With of these elements of the blood, with the water, fibrine, albumen, salts, fatty matter and corpuscles, the alcohol comes in-tuned when it enters the blood, and, if it’s in sufficient quantity, it produces disturbing action. I have watched this disturbance very carefully on the blood corpuscles; for, in some animals we tend to can see these floating along throughout life, and we tend to will also observe them from men who are beneath the effects of alcohol, by removing a speck of blood, and examining it with the microscope. The action of the alcohol, when it is observable, is varied. It could cause the corpuscles to run too closely along, and to stick in rolls; it may modify their define, creating the clear-outlined, smooth, environs irregular or crenate, or perhaps starlike; it may change the spherical corpuscle into the oval type, or, in very extreme cases, it may manufacture what I could decision a truncated form of corpuscles, in which the amendment is so great that if we did not trace it through all its stages, we tend to should be puzzled to understand whether the item looked at were indeed a blood-cell. Of these changes are due to the action of the spirit upon the water contained within the corpuscles; upon the capacity of the spirit to extract water from them. During each stage of modification of corpuscles so described, their perform to soak up and fix gases is impaired, and when the aggregation of the cells, in masses, is great, alternative difficulties arise, for the cells, united together, pass less easily than they should through the minute vessels of the lungs and of the overall circulation, and impede the present, by that local injury is produced.

“A further action upon the blood, instituted by alcohol in excess, is upon the fibrine or the plastic colloidal matter. On this the spirit may act in two totally different ways, according to the degree in which it affects the water that holds the fibrine in solution. It might fix the water with the fibrine, and therefore destroy the power of coagulation; or it could extract the water therefore determinately as to supply coagulation.”

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